In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Truncated Cables1 Causes agenesis of the corpus callosum in mice. FLP/frt system BALB/c-Cables1<tm1Utr> BALB/c-Cables1<tm1Utr> BALB-Cables1 KO BALB-Cables1 KO Cables1 gene null knockout mice. Exon 1 was replaced with a neo cassette. Homozygous mutant mice show no obvious abnormality. RBRC06318 C (3-6 months) Developmental Biology Research <a href='https://brc.riken.jp/mus/pcr06318'>Genotyping protocol -PCR-</a> 筑波大学生命科学動物資源センター・杉山文博先生(2014)。BALB/c由来ES細胞を用いて作出。 杉山 文博 true Homozygote x Homozygote [or Crossing to BALB/cAnNCrlCrlj] Homozygote x Homozygote [or Crossing to BALB/cAnNCrlCrlj] Fumihiro SUGIYAMA Cables1遺伝子のnullノックアウトマウス。エクソン1をneoカセットで置換。ホモマウスは目立った異常は認められない。脳梁欠損形質を示すTASマウス (RBRC06317) との交配によるF1マウスは脳梁欠損を呈す。生存性、繁殖性は正常。, Necessary documents for ordering:<ol><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol> 条件を付加する。<br>研究成果の公表にあたって寄託者の指定する文献を引用する。Truncated Cables1 Causes agenesis of the corpus callosum in mice. Mouse Cables1 genomic DNA, human phosphoglycerate kinase promoter (PGK promoter), E. coli Neomycin resistance gene, phage P1 loxP, yeast FRT sites Cables1遺伝子のnullノックアウトマウス。エクソン1をneoカセットで置換。ホモマウスは目立った異常は認められない。脳梁欠損形質を示すTASマウス (RBRC06317) との交配によるF1マウスは脳梁欠損を呈す。生存性、繁殖性は正常。 Developed by Fumihiro Sugiyama, Laboratory animal resource center, University of Tsukuba in 2014. BALB/c derived ES cells were used to generate the knockout mice. C(3〜6か月) Cre/loxP system